The role of female hormones on lung function in chronic lung diseases
BMC Women's Health 2011, 11:24
".....it is known that sex hormones such as estrogen can also up-regulate MUC5B gene expression in normal
human airway epithelial cells [82]. MUC5B is one of the major mucins in the human airway
submucosal glands [83]. Estrogen is not the only regulator of MUC5B but also regulates a wide
diversity of genes involved in extracellular matrix, general cell growth, and differentiation processes
[24]. Taken together, estradiol may have the potential to augment mucin production resulting in
reduced clearance in CF. "
Read more here: http://www.biomedcentral.com/content/pdf/1472-6874-11-24.pdf
No comments:
Post a Comment