Clinical Trials

I wanted to update you all on the newly listed clinical trials, as well as trials outside the US as I'm noticing I'm getting more and more visitors from around the globe. (*waves*)

• Multidose Safety and Tolerability Study of (Arikace™) for Inhalation In Cystic Fibrosis Patients in Alabama http://snipurl.com/dkr4e
• Assessment of Quadriceps Muscle Electrostimulation Used in Patients Suffering From Cystic Fibrosis (STIMUCO) in France http://snipurl.com/dkr8y

• Pharmacokinetics of Linezolid in Children With Cystic Fibrosis in Texas http://snipurl.com/dkrc0

• Treatment of Metabolic Alkalosis in Acute Exacerbations of Cystic Fibrosis in Australia http://snipurl.com/dkrgx

• Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QAU145 in Patients With Cystic Fibrosis in Alabama http://snipurl.com/dkrl3

• Vitamin D3 for the Treatment of Low Vitamin D in Cystic Fibrosis in Penn http://snipurl.com/dkrpy

• Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis, Mild Lung Disease, and P. Aeruginosa (AIR-CF4) all over the US and Canada and Australia (yes, they're still recruting) http://snipurl.com/dkrrm

• Do Musculoskeletal Techniques Improve Forced Expiratory Volume in One Second in Adults With Cystic Fibrosis? in London http://snipurl.com/dkrug

• SD Cystic Fibrosis Study in Minnesota and and PA http://snipurl.com/dkrz1

• Short Term Safety and Efficacy of Lubiprostone in Adults With Cystic Fibrosis http://snipurl.com/dks0m

More tomorrow when I finish my midterm :)


Done with the midterm. Here's some more:

• Ghrelin in Cystic Fibrosis (ghrelin) in Great Britain http://www.clinicaltrials.gov/ct2/show/NCT00763477?term=cystic+fibrosis&recr=Open&rank=16

• Early Intervention in Pulmonary Exacerbation in Cystic Fibrosis in Washington http://www.clinicaltrials.gov/ct2/show/NCT00850551?term=cystic+fibrosis&recr=Open&rank=18

• The Effect of Hypertonic Saline on the Lung Clearance Index in Patients With Cystic Fibrosis in Ontario http://www.clinicaltrials.gov/ct2/show/NCT00635141?term=cystic+fibrosis&recr=Open&rank=19

• Can Quantitative Ultrasound be Used for the Evaluation of Bone Health in Adolescents and Adults With Cystic Fibrosis in Belgium http://www.clinicaltrials.gov/ct2/show/NCT00221572?term=cystic+fibrosis&recr=Open&rank=20

• Inhaled Sodium Pyruvate for the Treatment of Cystic Fibrosis in Minnesota . http://www.clinicaltrials.gov/ct2/show/NCT00308243?term=cystic+fibrosis&recr=Open&rank=21

• Use of Formula Fortified With DHA in Infants With Cystic Fibrosis all over the US http://www.clinicaltrials.gov/ct2/show/NCT00530244?term=cystic+fibrosis&recr=Open&rank=23

• Non-Invasive Ventilation and Oxygen Therapy in Cystic Fibrosis Patients With Nocturnal Oxygen Desaturation Australia http://www.clinicaltrials.gov/ct2/show/NCT00157183?term=cystic+fibrosis&recr=Open&rank=24

• Coping Compliance and Adjustment in Adolescents With Cystic Fibrosis Ohio http://www.clinicaltrials.gov/ct2/show/NCT00577252?term=cystic+fibrosis&recr=Open&rank=25

• Prolonging the Duration of Peripheral Venous Catheters in Cystic Fibrosis People - Italy http://www.clinicaltrials.gov/ct2/show/NCT00418470?term=cystic+fibrosis&recr=Open&rank=26

• Capsule Endoscopy in Cystic Fibrosis - Israel http://www.clinicaltrials.gov/ct2/show/NCT00333957?term=cystic+fibrosis&recr=Open&rank=27

• The Effect of rhDNase on Ventilation Inhomogeneity in Patients With Cystic Fibrosis - Canada http://www.clinicaltrials.gov/ct2/show/NCT00557089?term=cystic+fibrosis&recr=Open&rank=28

• Utility of Induced Sputum Using Hypertonic Saline to Evaluate Infection and Inflammation in Cystic Fibrosis- Canada http://www.clinicaltrials.gov/ct2/show/NCT00721071?term=cystic+fibrosis&recr=Open&rank=29

• Anti-Pseudomonas IgY to Prevent Infections in Cystic Fibrosis (PseudIgY) - Sweden http://www.clinicaltrials.gov/ct2/show/NCT00633191?term=cystic+fibrosis&recr=Open&rank=32

• Treatment of Aspergillus Fumigatus (a Fungal Infection) in Patients With Cystic Fibrosis - Canada http://www.clinicaltrials.gov/ct2/show/NCT00528190?term=cystic+fibrosis&recr=Open&rank=33

• A Phase II , Placebo-Controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Cystic Fibrosis (INCA) - all around Europe http://www.clinicaltrials.gov/ct2/show/NCT00757848?term=cystic+fibrosis&recr=Open&rank=34

• Modulation by Sex Hormones of Inflammation and Susceptibility to Pseudomonas Aeruginosa in Cystic Fibrosis Airways - Canada http://www.clinicaltrials.gov/ct2/show/NCT00700050?term=cystic+fibrosis&recr=Open&rank=35

• Lancovutide (Moli1901) Inhalation Solution Study in Adolescents and Adults With Cystic Fibrosis - Austria http://www.clinicaltrials.gov/ct2/show/NCT00671736?term=cystic+fibrosis&recr=Open&rank=37

• Efficacy of Bucelipase Alfa (BSSL) in Patients With Cystic Fibrosis and Pancreatic Insufficiency- Netherlands and Poland http://www.clinicaltrials.gov/ct2/show/NCT00743483?term=cystic+fibrosis&recr=Open&rank=38

• Effect of Pioglitazone on Inflammation in Cystic Fibrosis - Los Angeles http://www.clinicaltrials.gov/ct2/show/NCT00719381?term=cystic+fibrosis&recr=Open&rank=39

• 18FDG-PET Imaging to Detect Changes in Airways Inflammation in Cystic Fibrosis Patients - Canada http://www.clinicaltrials.gov/ct2/show/NCT00684346?term=cystic+fibrosis&recr=Open&rank=41

• Aztreonam for Inhalation Solution Versus Tobramycin Nebuliser Solution in Patients With Cystic Fibrosis and P. Aeruginosa, Followed by an Open-Label, Single Arm Extension - all over Europe http://www.clinicaltrials.gov/ct2/show/NCT00757237?term=cystic+fibrosis&recr=Open&rank=42

• Nutritional, Metabolic and Respiratory Status in Cystic Fibrosis- France http://www.clinicaltrials.gov/ct2/show/NCT00476281?term=cystic+fibrosis&recr=Open&rank=43

• Aztreonam Lysine for Inhalation in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Airway Infection - all over the United States (still actively recruiting!!!!!!) http://www.clinicaltrials.gov/ct2/show/NCT00499720?term=cystic+fibrosis&recr=Open&rank=45&show_locs=Y#locn

• Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection- Alaska, Nevada, Oklahoma http://www.clinicaltrials.gov/ct2/show/NCT00794586?term=cystic+fibrosis&recr=Open&rank=46

• An Exploratory Study to Assess Multiple Doses of Omalizumab in Patients Aged 12 Years and Older With Cystic Fibrosis Complicated by Allergic Bronchopulmonary Aspergillosis - Belgium http://www.clinicaltrials.gov/ct2/show/NCT00787917?term=cystic+fibrosis&recr=Open&rank=47

• Do Physiotherapy Techniques Improve Posture During Admission for a Chest Infection in Adults With Cystic Fibrosis? - Great Britain http://www.clinicaltrials.gov/ct2/show/NCT00806884?term=cystic+fibrosis&recr=Open&rank=48

• 18FDG- PET/CT Contribution to the Assessment of Lesion Severity in Cystic Fibrosis (CF) - Israel http://www.clinicaltrials.gov/ct2/show/NCT00363402?term=cystic+fibrosis&recr=Open&rank=49

• A Study of the Efficacy and Tolerability of Pancrelipase Microtablet (MT) Capsules for the Treatment of Cystic Fibrosis-Dependent Exocrine Pancreatic Insufficiency - Oklahoma http://www.clinicaltrials.gov/ct2/show/NCT00662675?term=cystic+fibrosis&recr=Open&rank=50

• Dissection of Staphylococcus Aureus Infection From Colonization in Cystic Fibrosis Patients (StaphCI) - Germany http://www.clinicaltrials.gov/ct2/show/NCT00669760?term=cystic+fibrosis&recr=Open&rank=51

• Dose Escalation Study of KB001 in Cystic Fibrosis Patients Infected With Pseudomonas Aeruginosa - all over the US http://www.clinicaltrials.gov/ct2/show/NCT00638365?term=cystic+fibrosis&recr=Open&rank=52

• ALTU-135 Efficacy Trial in Patients With Cystic Fibrosis-Related Exocrine Pancreatic Insufficiency - all over the US http://www.clinicaltrials.gov/ct2/show/NCT00449878?term=cystic+fibrosis&recr=Open&rank=54

• Magnetic Resonance Imaging (MRI) for Early Diagnosis of Cystic Fibrosis (CF) - Germany http://www.clinicaltrials.gov/ct2/show/NCT00760071?term=cystic+fibrosis&recr=Open&rank=55

• IGF-1 Therapy in Patients With Cystic Fibrosis New York http://www.clinicaltrials.gov/ct2/show/NCT00566241?term=cystic+fibrosis&recr=Open&rank=56

• Choline Nutrition in Children With Cystic Fibrosis (CF) - Canada http://www.clinicaltrials.gov/ct2/show/NCT00686361?term=cystic+fibrosis&recr=Open&rank=57

• Infant Study of Inhaled Saline in Cystic Fibrosis - all across the US http://www.clinicaltrials.gov/ct2/show/NCT00709280?term=cystic+fibrosis&recr=Open&rank=58

• FDG-PET Imaging in Young Cystic Fibrosis Patients - Missouri http://www.clinicaltrials.gov/ct2/show/NCT00846053?term=cystic+fibrosis&recr=Open&rank=59

• Ocular Surface Changes in Patients With Cystic Fibrosis - Poland http://www.clinicaltrials.gov/ct2/show/NCT00345280?term=cystic+fibrosis&recr=Open&rank=61

• The Short Term Safety and Efficacy of Inhaled L-Arginine in Patients With Cystic Fibrosis - Canada http://www.clinicaltrials.gov/ct2/show/NCT00405665?term=cystic+fibrosis&recr=Open&rank=64

• Efficacy and Safety Study of Inhaled Glutathione in Cystic Fibrosis Patients - Germany http://www.clinicaltrials.gov/ct2/show/NCT00506688?term=cystic+fibrosis&recr=Open&rank=65

• NAC Phase IIB: A Multi-Center, Phase IIB, Randomized, Placebo-Controlled, Double-Blind Study Of The Effects Of N-Acetylcysteine On Redox Changes and Lung Inflammation In Cystic Fibrosis Patients - CA http://www.clinicaltrials.gov/ct2/show/NCT00809094?term=cystic+fibrosis&recr=Open&rank=66

• Sleep in Patients With Cystic Fibrosis (Sommeil) - France http://www.clinicaltrials.gov/ct2/show/NCT00804661?term=cystic+fibrosis&recr=Open&rank=68

• Prevalence of Chronic Rhinosinusitis, Germ-Colonisation and Ability to Smell in Cystic Fibrosis - Germany http://www.clinicaltrials.gov/ct2/show/NCT00803881?term=cystic+fibrosis&recr=Open&rank=69

• Effects of Vitamin D Supplementation on Lung Function in an Acute Pulmonary Exacerbation of Cystic Fibrosis - Georgia http://www.clinicaltrials.gov/ct2/show/NCT00788138?term=cystic+fibrosis&recr=Open&rank=72

• Study on the Efficacy of Slow Release Insulin in Cystic Fibrosis Patients With Glucide Intolerance and Clinical Decay- Italy http://www.clinicaltrials.gov/ct2/show/NCT00687466?term=cystic+fibrosis&recr=Open&rank=73

• Genetic Modifiers of Cystic Fibrosis: Sibling Study - Maryland http://www.clinicaltrials.gov/ct2/show/NCT00037778?term=cystic+fibrosis&recr=Open&rank=76

• Early Diagnosis of Diabetes Mellitus in Patients With Cystic Fibrosis - all over Europe http://www.clinicaltrials.gov/ct2/show/NCT00662714?term=cystic+fibrosis&recr=Open&rank=78

• Miglustat in Cystic Fibrosis- Belgium http://www.clinicaltrials.gov/ct2/show/NCT00742092?term=cystic+fibrosis&recr=Open&rank=80

• Nasal Inhalation of Tobramycin in Patients With Cystic Fibrosis and Pseudomonas Aeruginosa Colonization - Germany http://www.clinicaltrials.gov/ct2/show/NCT00774072?term=cystic+fibrosis&recr=Open&rank=82

• Study About Complications of Totally Implanted Venous Access Devices (TIVADs) in People With Cystic Fibrosis (CF) - Italy http://www.clinicaltrials.gov/ct2/show/NCT00670579?term=cystic+fibrosis&recr=Open&rank=83

• Biodistribution of Neutrophile Proteases in the Sputum of Patients Affected by Cystic Fibrosis (Pro-Muco) - France http://www.clinicaltrials.gov/ct2/show/NCT00750932?term=cystic+fibrosis&recr=Open&rank=84

• Phase II Study of the Safety and Efficacy of Inhaled Alpha-1 Antitrypsin (AAT ) in Cystic FibrosisPatients - Israel http://www.clinicaltrials.gov/ct2/show/NCT00499837?term=cystic+fibrosis&recr=Open&rank=90

• CFF Biomarkers of Exacerbation - all over the US http://www.clinicaltrials.gov/ct2/show/NCT00788359?term=cystic+fibrosis&recr=Open&rank=91

• Study of Tauroursodeoxycholic Acid for Hepatobiliary Disease in Cystic Fibrosis - Colorado, Ohio and Italy http://www.clinicaltrials.gov/ct2/show/NCT00004441?term=cystic+fibrosis&recr=Open&rank=94

• Study of Hepatic Glucose Production and De Novo Lipogenesis in Patients With Cystic Fibrosis - Texas and Utah http://www.clinicaltrials.gov/ct2/show/NCT00014781?term=cystic+fibrosis&recr=Open&rank=95

• Randomized Study of Alendronate in Adult Patients With Cystic Fibrosis Related Osteoporosis - North Carolina http://www.clinicaltrials.gov/ct2/show/NCT00004489?term=cystic+fibrosis&recr=Open&rank=96

• Long-Term Study, Comparing Vest Therapy to Positive Expiratory Pressure (PEP) Therapy in the Treatment of Cystic Fibrosis - Canada (maybe a chance for you Canadians to get a hold of a Vest!!!) http://www.clinicaltrials.gov/ct2/show/NCT00817180?term=cystic+fibrosis&recr=Open&rank=97

• Zinc Homeostasis and Kinetics in Children With Cystic Fibrosis (CF) - Texas http://www.clinicaltrials.gov/ct2/show/NCT00104494?term=cystic+fibrosis&recr=Open&rank=99

• Cystic Fibrosis (CF) Leukocyte Genes as Biomarkers for Novel Therapies - Colorado http://www.clinicaltrials.gov/ct2/show/NCT00727285?term=cystic+fibrosis&recr=Open&rank=103

• Quantification of Pulmonary Neutrophil Activity in Cystic Fibrosis Using Radiolabeled Fluorodeoxyglucose and PET Imaging - Missouri http://www.clinicaltrials.gov/ct2/show/NCT00023465?term=cystic+fibrosis&recr=Open&rank=104

• Role of Toxins in Lung Infections Caused by Pseudomonas Aeruginosa - Maryland, Washington and Wisconsin http://www.clinicaltrials.gov/ct2/show/NCT00027183?term=cystic+fibrosis&recr=Open&rank=105

• Use of a Biofilm Antimicrobial Susceptibility Assay to Guide Antibiotic Therapy - Canada http://www.clinicaltrials.gov/ct2/show/NCT00786513?term=cystic+fibrosis&recr=Open&rank=112

• Safety, Tolerability and Efficacy of MP-376 Given for 28 Days to Cystic Fibrosis (CF) Patients - all over the US, Germany and the Netherlands http://www.clinicaltrials.gov/ct2/show/NCT00677365?term=cystic+fibrosis&recr=Open&rank=114

• Investigating Mucinase Activity in Airway Disease - CA http://www.clinicaltrials.gov/ct2/show/NCT00596232?term=cystic+fibrosis&recr=Open&rank=128